Breast cancer cells taken out during a biopsy or surgery will be tested to see if they have certain proteins that are estrogen or progesterone receptors. When the hormones estrogen and progesterone attach to these receptors, they fuel the cancer growth. Cancers are called hormone receptor-positive or hormone receptor-negative based on whether or not they have these receptors proteins. Knowing the hormone receptor status is important in deciding treatment options. Receptors are proteins in or on cells that can attach to certain substances in the blood.
What Is Hormonal Therapy?
Breast cancer types: What your type means - Mayo Clinic
The Gordon Research Conference GRC on Hormone-Dependent Cancers: Mechanisms to Tailored Therapeutics August , Sunday River Resort, Newry, ME , will bring together an outstanding faculty of new and more established scientists and translational researchers to explore molecular mechanisms of disease and strategize about new targeted therapies for hormone-dependent cancers. Hormones influence not only breast and prostate cancer, the two most common hormone-dependent cancers, but also have a major impact on less common hormone-sensitive malignancies e. Developing a means to more specifically treat and ideally prevent hormone-dependent cancers is of critical importance given the significant impact these malignancies have on human health and the economic burden of disease. An in depth understanding of hormone action in regulating diverse cellular processes, cancer phenotypes and drug responsiveness is essential for the development of effective and well tolerated treatment strategies.
ER-Positive Breast Cancer: Prognosis, Life Expectancy, and More
Your pathology report will include the results of a hormone receptor assay, a test that tells you whether or not the breast cancer cells have receptors for the hormones estrogen and progesterone. Hormone receptors are proteins — found in and on breast cells — that pick up hormone signals telling the cells to grow. This suggests that the cancer cells, like normal breast cells, may receive signals from estrogen that could promote their growth.